mriselMagnetic Resonance in SolidsMagnetic Resonance in Solids2072-5981Kazan Federal Universitymrisel-152Research ArticleСтатьиtherosclerotic plaque and hydroxyapatite nanostructures studied by high-frequency EPRGafurovM. R.

Institute of Physics, Kazan 420008

YavkinB. V.

Institute of Physics, Kazan 420008

BiktagirovT. B.

Institute of Physics, Kazan 420008

MaminG. V.

Institute of Physics, Kazan 420008

OrlinskiiS. B.

Institute of Physics, Kazan 420008

Sergei.Orlinskii@kpfu.ruIzotovV. V.

Institute of Physics, Kazan 420008

SalakhovM. Kh.

Institute of Physics, Kazan 420008

KlimashinaE. S.

Moscow 119992

PutlayevV. I.

Moscow 119992

Abdul'yanovV. A.

Kazan 420101

IgnatjevI. M.

Kazan 420101

KhairullinR. N.

Kazan 420101

ZamochkinA. V.

Kazan 420101

ChelyshevYu. A.

Kazan 420008; 420012 Kazan

Kazan Federal UniversityRussian FederationM.V. Lomonosov Moscow State University, Department of ChemistryRussian FederationInterregional Clinic and Diagnostic CenterRussian FederationKazan Federal University, Institute of Physics; Kazan State Medical UniversityRussian Federation20131901202415113102 (7 pp.)Copyright © Gafurov M.R., Yavkin B.V., Biktagirov T.B., Mamin G.V., Orlinskii S.B., Izotov V.V., Salakhov M.K., Klimashina E.S., Putlayev V.I., Abdul'yanov V.A., Ignatjev I.M., Khairullin R.N., Zamochkin A.V., Chelyshev Y.A., 20242024Gafurov M.R., Yavkin B.V., Biktagirov T.B., Mamin G.V., Orlinskii S.B., Izotov V.V., Salakhov M.K., Klimashina E.S., Putlayev V.I., Abdul'yanov V.A., Ignatjev I.M., Khairullin R.N., Zamochkin A.V., Chelyshev Y.A.Gafurov M.R., Yavkin B.V., Biktagirov T.B., Mamin G.V., Orlinskii S.B., Izotov V.V., Salakhov M.K., Klimashina E.S., Putlayev V.I., Abdul'yanov V.A., Ignatjev I.M., Khairullin R.N., Zamochkin A.V., Chelyshev Y.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.mrsej.ru/jour/article/view/152

A series of nanosized (20 nm and larger) samples of hydroxyapatite powders synthesized by wet preparation method and doped with Mn2+ and Pb2+ ions were studied by 94 GHz pulsed electron paramagnetic resonance (EPR). The results are compared with those obtained in the samples of aorta walls from male patients with atherosclerosis as well as in bulk hydroxyapatite materials. It is shown that in contrast to bulk materials Pb ions at least partially replace the Ca(1) site in the hydroxyapatite structure. The spectral characteristics of the Mn2+ ions revealed in atherosclerotic plaque and synthetic hydroxyapatite are found to be practically identical. The hypothesis about the important role of (nano)hydroxyapatite in formation and rupture of atherosclerotic plaques is supported.

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The authors declare that there are no conflicts of interest present.